Safety/Irritation / Antioxidant30%qualità VERY_LOW (non umano o non classificabile, da revisionare)LIV-0043
TPGS Modified Phospholipid-free and Cholesterol-free Ethosomes Enhance Chemical Stability and Transdermal Permeation Of Retinol.
Fenoteca
EU entry #24134 · fonte CosIng
RETINOL
P1 · deepL4 · evidenza umana
- CAS
- 68-26-8 / 11103-57-4
- EC
- 200-683-7 / 234-328-2
- Evidenze
- 18
- Confidenza max
- 0.20
SKIN CONDITIONINGSKIN CONDITIONING - MISCELLANEOUS
Profilo di predizione
Valore e confidenza sono output separati (regola R04); ogni riga è tracciabile alla sua base (R07).
Conoscenza diretta / funzionale
Stratum corneum hydrationconfidenza bassa
basi: CosIng function=SKIN CONDITIONING; prior_strength=0.1 — evidenze 0 · coefficienti 0
Agente di ricerca live
Cerca ulteriore letteratura per questa voce (Europe PMC + PubChem, estrazione abstract-only, tutto etichettato «da revisionare»).ultimo esito: evidenza diretta trovata
Proprietà chimico-fisiche
Fonte PubChem via agente live — valori calcolati/derivati, da revisionare.
- inchikey
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N
- molecular formula
- C20H30O
- molecular weight
- 286.5 g/mol
- xlogp
- 5.7
Evidenze citate
Soothing/Anti-inflammatory / Safety/Irritation / Antioxidant1.1% / 0.8% / 1.8% / 2.4%qualità VERY_LOW (non umano o non classificabile, da revisionare)LIV-0044
Development and Evaluation of Retinol-Curcumin Nanoemulsions for Potential Topical Delivery
in vitro
Soothing/Anti-inflammatory / Wrinkles / Safety/Irritation / Collagen/ECM / Antioxidantqualità VERY_LOW (non umano o non classificabile, da revisionare)LIV-0045
Rosemary Aqueous Extract as a Natural Alternative to Retinol for Skin Aging Intervention.
in vitro; ex vivo / RHE
Soothing/Anti-inflammatory / Safety/Irritationqualità VERY_LOW (non umano o non classificabile, da revisionare)LIV-0046
Epalrestat repurposing for psoriasis: Targeting AKR1B10 to modulate the metabolic-immune axis via restoring retinol metabolism and suppressing IL-17 signaling.
Barrier/TEWL / Wrinkles2.3% / 29.0% / 10.6% / 18.4%qualità VERY_LOW (non umano o non classificabile, da revisionare)LIV-0048
Retinol-Loaded Mannosylerythritol Lipid Nanoliposome for Enhanced Human Skin Penetration.
Acnequalità VERY_LOW (non umano o non classificabile, da revisionare)LIV-0049
Tailored dual release of retinol and salicylic acid from salicylate-based poly(anhydride-ester) microspheres with tunable degradation profiles.
Unspecifiedqualità Unreviewed (AI)LIT-0168
Round Table Discussion: Aesthetic Treatment Considerations for the Perimenopausal & Menopausal Patient (J Cosmet Dermatol, 2026)
Unspecifiedqualità Unreviewed (AI)LIT-0169
The Next Generation of Skin Care: Transforming Retinoid Therapeutics (Cells, 2025)
Unspecifiedqualità Unreviewed (AI)LIT-0170
A Topical Cosmeceutical Approach to Submental Fullness in Indian Women: 12-Week Prospective Study (J Cosmet Dermatol, 2026)
Unspecifiedqualità Unreviewed (AI)LIT-0171
Retinoids in scarless skin regeneration: from molecular mechanisms to therapeutic strategies (Front Cell Dev Biol, 2025)
Unspecifiedqualità Unreviewed (AI)LIT-0172
Topical medium-length PDRN enhances dermal extracellular matrix repair in photodamaged skin via PI3K-Akt/TGF-β-regulated pathways (PLoS One, 2026)
Acnequalità Unreviewed (AI)LIT-0173
A Novel Retinoid and Salicylic Acid Topical Treatment for Moderate-Severe Acne (J Drugs Dermatol, 2026)
Photoprotectionqualità Unreviewed (AI)LIT-0174
Prospective, Double‐Blind, Vehicle‐Controlled Assessment of Topical Bakuchiol on Photoaging in a Chinese Population (J Cosmet Dermatol, 2026)
Overall aging skin / hydration / wrinkles0.15% vs 0.3%qualità MediumEV-0003
Both concentrations improved overall condition; no significant difference between 0.15% and 0.3% at 8 weeks
Human pilot; within-face comparison · n=40 total across two sites · 8 weeks daily
Hydration / Barrier/TEWL / Pigmentation / Soothing/Anti-inflammatory / Wrinkles / Safety/Irritation0.5% / 9.45% / 4.11% / 3.88%qualità MODERATE (abstract-only, da revisionare)LIV-0051
A prospective, double-blinded, randomized head-to-head clinical trial of topical adapinoid (oleyl adapalenate) versus retinol.
randomized controlled; double-blind; clinical (human) · 12 weeks (da abstract)
Hydration / Barrier/TEWL / Safety/Irritation / Antioxidant61.5%qualità LOW (abstract-only, da revisionare)LIV-0042
An Innovative Dendrimer-Based Retinol Delivery System for Xerosis Care: Stability, Tolerance, and Sustained Hydration.
clinical (human) · 28 days (da abstract)
Hydration / Barrier/TEWL / Sebum / Soothing/Anti-inflammatory / Wrinkles / Acne / Antioxidantqualità LOW (abstract-only, da revisionare)LIV-0047
Dynamic multi-omics mechanisms underpinning retinol tolerance: stage-specific reconstruction of skin barrier function and host-microbiome metabolic interactions.
clinical (human)
Soothing/Anti-inflammatory / Acne / Safety/Irritationqualità LOW (abstract-only, da revisionare)LIV-0050
SAPHO Syndrome Presenting With Severe Inflammatory Back Pain (Sacroiliitis) and Rare Retinol Associated Myopathy in an Iraqi Adolescent Male: A Case Report and Literature Review.
review; clinical (human)
Fonte identità: CosIng (Commissione Europea). Questa scheda è uno strumento professionale di esplorazione: non è un giudizio sul prodotto finito né una valutazione di sicurezza.