EU entry #2176 · fonte CosIng

ARBUTIN

P1 · deepL3 · inferenza funzionale

CAS: 497-76-7
EC: 207-850-3
Evidenze: 8
Confidenza max: 0.65

ANTIOXIDANTBLEACHINGSKIN CONDITIONING - MISCELLANEOUS

Profilo di predizione

Valore e confidenza sono output separati (regola R04); ogni riga è tracciabile alla sua base (R07).

Conoscenza diretta / funzionale

Oxidative stressconfidenza alta

basi: CosIng function=ANTIOXIDANT; prior_strength=0.7 — evidenze 0 · coefficienti 0

Pigmentation/melaninconfidenza alta

basi: CosIng function=BLEACHING; prior_strength=0.65 — evidenze 0 · coefficienti 0

Agente di ricerca live

Cerca ulteriore letteratura per questa voce (Europe PMC + PubChem, estrazione abstract-only, tutto etichettato «da revisionare»).

Evidenze citate

Pigmentationqualità Unreviewed (AI)LIT-0017

Efficacy and Safety Evaluation of Microneedling Combined with Tranexamic Acid-Arbutin Liquid Excipients in the Treatment of Melasma: A Retrospective Study. (Clin Cosmet Investig Dermatol, 2025)

retrospective study

PMID 41321592 DOI

Pigmentationqualità Unreviewed (AI)LIT-0018

Effectiveness and Safety of Combined Use of Home-Based Radiofrequency Device and Arbutin Cream in Melasma and Facial Rejuvenation. (J Cosmet Dermatol, 2025)

PMID 39918262 DOI

Pigmentationqualità Unreviewed (AI)LIT-0019

Efficacy and Safety of a Topical Formulation Containing Trihydroxybenzoic Acid Glucoside and α-Arbutin, Applied Along With a Sunscreen: A Noncomparative, Prospective, Interventional Study in Indian Females With Facial Melasma or Dark Spots. (J Cosmet Dermatol, 2025)

noncomparative prospective interventional study

PMID 39943675 DOI

Pigmentation5%qualità Unreviewed (AI)LIT-0020

The Efficacy of Topical Cosmetic Containing Alpha-Arbutin 5% and Kojic Acid 2% Compared With Triple Combination Cream for the Treatment of Melasma: A Split-Face, Evaluator-Blinded Randomized Pilot Study. (J Cosmet Dermatol, 2025)

split-face evaluator-blinded randomized pilot study

PMID 39555866 DOI

Safety/Irritationqualità Unreviewed (AI)LIT-0021

Toxicological evaluation of α-Arbutin, a skin depigmenting agent, with emphasis on mutagenicity assessment. (Food Chem Toxicol, 2026)

PMID 42173470 DOI

Pigmentationqualità Unreviewed (AI)LIT-0022

Evidence for Arbutin in Skincare: Maintenance of Melasma. (Skinmed, 2023)

PMID 38051235

Pigmentationqualità Unreviewed (AI)LIT-0023

Arbutin as a Skin Depigmenting Agent with Antimelanogenic and Antioxidant Properties. (Antioxidants (Basel), 2021)

PMID 34356362 DOI

Photoprotectionqualità Unreviewed (AI)LIT-0024

The Effect of α-Arbutin on UVB-Induced Damage and Its Underlying Mechanism. (Molecules, 2024)

PMID 38731413 DOI

Fonte identità: CosIng (Commissione Europea). Questa scheda è uno strumento professionale di esplorazione: non è un giudizio sul prodotto finito né una valutazione di sicurezza.